122347-90-4

Basic information

• Product Name: p-nitrobenzyl (2R,3R)-2-(2'-formylmethylthio)-4-oxo-3-phenoxyacetylaminoazetidine-1-oxalate
• Synonyms: p-nitrobenzyl (2R,3R)-2-(2'-formylmethylthio)-4-oxo-3-phenoxyacetylaminoazetidine-1-oxalate
• CAS NO: 122347-90-4
• Molecular Weight: 501.474
• Mol File: 122347-90-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: p-nitrobenzyl (2R,3R)-2-(2'-formylmethylthio)-4-oxo-3-phenoxyacetylaminoazetidine-1-oxalate(CAS DataBase Reference)
• NIST Chemistry Reference: p-nitrobenzyl (2R,3R)-2-(2'-formylmethylthio)-4-oxo-3-phenoxyacetylaminoazetidine-1-oxalate(122347-90-4)
• EPA Substance Registry System: p-nitrobenzyl (2R,3R)-2-(2'-formylmethylthio)-4-oxo-3-phenoxyacetylaminoazetidine-1-oxalate(122347-90-4)

Safety Data

• Hazardous Substances Data: 122347-90-4(Hazardous Substances Data)

Upstream product

• 64370-08-7 p-nitrobenzyl (2R,3R)-2-(benzothiazol-2'-yldithio)-α-isopropylidene-4-oxo-3-phenoxyacetylaminoazetidine-1-acetate 
• 122347-85-7 p-nitrobenzyl (2R,3R)-2-allythio-α-isopropylidene-4-oxo-3-phenoxyacetylaminoazetidine-1-acetate 

Downstream Products

• 619-73-8 4-nitrobenzyl chloride 
• 64836-37-9 p-nitrobenzyl (2R,3R)-7-phenoxyacetylaminoceph-3-em-4-carboxylate 
• 122347-91-5 2-phenoxymethyl-4-(2'-methylprop-1'-enylaminocarbonyl-1'-nitrobenzyloxycarbonyl)thiazole 

Relevant articles and documents

A New Preparative Route to 3-Unsubstituted Cephalosporins from Penicillin V

p-Nitrobenzyl (2R,3R)-2-(benzothiazol-2'-yldithio)-α-isopropylidene-4-oxo-3-phenoxyacetylaminoazetidine-1-acetate (7), readily prepared from penicillin V, can be converted into the corresponding 2-allylthio compound (2) by addition of allyl bromide and sodium borohydride at a low temperature.This compound (2) on treatment with ozone, followed by cyclization with trimethyl phosphite, produces a 3H-ceph-3-em ester (4).The ester can be easily de-esterified to the free acid (1b).