1224199-14-7Relevant articles and documents
Tritylium assisted iodine catalysis for the synthesis of unsymmetrical triarylmethanes
Boyarskaya, Dina V.,Courant, Thibaut,Lombard, Marine,Masson, Géraldine,Neuville, Luc
supporting information, p. 6502 - 6508 (2020/09/09)
The combined Lewis acid catalytic system, generated from molecular iodine and tritylium tetrafluoroborate effectively catalyzed the Friedel-Crafts (FC) arylation of diarylmethyl sulfides providing an efficient access to various unsymmetrical triarylmethanes. The addition of tritylium and iodine created a more active catalytic system to promote the cleavage of sulfidic C-S bonds. This journal is
Iron-catalyzed friedel-crafts benzylation with benzyl TMS ethers at room temperature
Sawama, Yoshinari,Shishido, Yuko,Kawajiri, Takahiro,Goto, Ryota,Monguchi, Yasunari,Sajiki, Hironao
supporting information, p. 510 - 516 (2014/04/03)
Friedel-Crafts benzylations between unactivated arenes and benzyl alcohol derivatives are clean and straightforward processes to construct biologically useful di- and triarylmethanes. We have established an efficient iron-catalyzed Friedel-Crafts benzylation method at room temperature that uses benzyl TMS ethers as substrates, which are poorly reactive under common nucleophilic substitution conditions. The reaction seems to progress through iron-catalyzed self-condensation of the benzyl TMS ether to the corresponding dibenzylic ether. The use of excess arene relative to benzyl TMS ether produced mono-benzylated arene (diand tri-arylmethane products), whereas the use of excess benzyl TMS ether versus arene provided bis-benzylated arene (polyarylated products) in high yields and regioselectivities. In previous methods, the latter double Friedel-Crafts benzylations hardly proceed.
Microwave-accelerated alkylation of arenes/heteroarenes with benzylic alcohols using antimony(III) chloride as catalyst: Synthesis of O-heterocycles
Shukla, Prashant,Choudhary, Manoj K.,Nayak, Sandip K.
supporting information; experimental part, p. 1585 - 1591 (2011/08/03)
An efficient protocol for alkylation of electron-rich arenes/heteroarenes with benzylic alcohols under microwave irradiation using antimony(III) chloride as catalyst has been developed. The mild reaction conditions, high yields, operational simplicity, and applicability to various substrates render the approach a useful route for the synthesis of diaryl/triarylalkane. In addition, a new route for the conversion of ortho-alkenylated phenols into functionalized O-heterocycles has been accomplished. Georg Thieme Verlag Stuttgart ? New York.
