122454-29-9 Usage
Description
4-Bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile is a halogenated pyrrole-based compound characterized by the presence of a bromine atom at the 4-position, a chlorine atom at the 4-phenyl group, a trifluoromethyl group at the 5-position, and a nitrile group at the 3-position. It belongs to the class of pyrroles, which are heterocyclic compounds with a wide range of applications in various industries due to their unique chemical properties.
Uses
Used in Pest Control Applications:
4-Bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile is used as an active ingredient in the development of pro-insecticides. It functions by metabolizing into an active insecticide after entering the host, providing effective pest control.
Used in Marine Antifouling Coatings:
In the marine industry, 4-Bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile is used as a marine antifouling agent. It is incorporated into antifouling coatings applied to boat hulls, oil rig structures, and drilling platform legs that are submerged underwater. The compound helps control the growth of barnacles and other invertebrate animal fouling organisms, reducing the negative impact on the performance and efficiency of these structures.
Used in Pharmaceutical Research:
Due to its unique chemical structure, 4-Bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile may also hold potential in the pharmaceutical industry as a starting material for the synthesis of new drugs or drug candidates. Its specific application in this field would depend on further research and development to explore its biological activities and potential therapeutic uses.
preparation
Tralopyril is an important intermediate in the synthesis of carbofuran, and bromine is the core raw material for the synthesis of Tralopyril. Tralopyril is a pyrrole resulting from the N-dealkylation of the ethoxymethyl group of chlorfenapyr. Chlorfenapyr is the first commercial proinsecticide developed by introducing ethoxymethyl group into the pyrrole N of tralopyril.
Check Digit Verification of cas no
The CAS Registry Mumber 122454-29-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,4,5 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 122454-29:
(8*1)+(7*2)+(6*2)+(5*4)+(4*5)+(3*4)+(2*2)+(1*9)=99
99 % 10 = 9
So 122454-29-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H5BrClF3N2/c13-9-8(5-18)10(19-11(9)12(15,16)17)6-1-3-7(14)4-2-6/h1-4,19H
122454-29-9Relevant articles and documents
Preparation method of trobiglide
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Paragraph 0026-0027, (2022/01/12)
The present invention discloses a method of preparation of trilobiril, specifically related to the field of agricultural technology, the preparation method provided by the present invention comprises the following steps: step 1, p-chlorobenzonitrile disso
Application of 2-aryl substituted pyrrole compound in medicine for killing oncomelania hupensis
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Paragraph 0148; 0158; 0159, (2019/01/08)
The invention relates to an application of 2-aryl substituted pyrrole compound in a medicine for killing oncomelania hupensis and belongs to the technical field of prevention and treatment of bilharziasis, and particularly provides the chemical structure of the 2-aryl substituted pyrrole compound and a preparation method of same. The 2-aryl substituted pyrrole compound, being an active component,is used for preparing the snail killing agent in the forms of suspending agents, emulsions and micro-emulsions for killing the oncomelania hupensis. Immersion killing use amount of the 2-aryl substituted pyrrole compound being the active component of the snail killing agent is 0.1-10.00 mg/l, and immersion killing time is 24-72 h. The use amount of spray application is 1-10 g/m and action timeis 3-7 days. Experiment proves that the 2-aryl substituted pyrrole compound has killing activity on the oncomelania hupensis and is lower than a snail killing agent, niclosamide, in the prior art in toxicity on aquatic organisms. The compound can be processed to prepare the snail killing agents and applied in the field of prevention and treatment of bilharziasis.
PRODUCTION OF ARYLPYRROL COMPOUNDS IN THE PRESENCE OF DIPEA BASE
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Page/Page column 14-15, (2018/10/19)
The invention relates to a process for the production of compounds of formula (I), comprising Step A of reacting compounds of formula (II) with 2,3-dihalopropionitrile or 2-haloacrylonitrile in the presence of DIPEA. It also relates to a process for the production of compounds of formula (III), comprising Step B of reacting compounds of formula (I) with Br2 in the presence of DIPEA. It also relates to a process C for the production of compounds of formula (IV), comprising Step C of reacting compounds of formula (III) with di(C1-C4-alkoxy)methane and either POCl3, or a mixture comprising POCl3 and DMF, in the presence of DIPEA. It also relates to the use of DIPEA as a base in the production of compounds of formula (I), compounds of formula (III) or compounds of formula (IV).
