122457-31-2 Usage
Description
2-Amino-8-methyl-3-(trideuteromethyl)imidazo[4,5-f]quinoxaline, also known as A606600, is a crystalline solid with a unique chemical structure. It is a labeled form of the heterocyclic amine MeIQx, which is a compound found in cooked meat and has been identified as a mutagen. 2-Amino-8-methyl-3-(trideuteromethyl)imidazo[4,5-f]quinoxaline has been extensively studied for its potential role in colorectal adenoma recurrence and its mutagenicity.
Uses
Used in Research and Development:
2-Amino-8-methyl-3-(trideuteromethyl)imidazo[4,5-f]quinoxaline is used as a research compound for studying the effects of heterocyclic amines, particularly MeIQx, on human health. Its application in this field is crucial for understanding the mechanisms of colorectal adenoma recurrence and the role of dietary mutagens in cancer development.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Amino-8-methyl-3-(trideuteromethyl)imidazo[4,5-f]quinoxaline is used as a reference compound for the development of new drugs and therapies targeting colorectal adenoma and other related cancers. Its unique properties make it a valuable tool for drug discovery and the design of novel treatment strategies.
Used in Food Safety and Quality Control:
2-Amino-8-methyl-3-(trideuteromethyl)imidazo[4,5-f]quinoxaline is also used in the food industry for safety and quality control purposes. It serves as a reference material for the detection and quantification of heterocyclic amines in cooked meat products, helping to ensure the safety and quality of these products for consumers.
Used in Toxicology Studies:
In toxicology, 2-Amino-8-methyl-3-(trideuteromethyl)imidazo[4,5-f]quinoxaline is used as a model compound to study the toxic effects of heterocyclic amines on human health. This helps researchers understand the potential risks associated with the consumption of cooked meat products and develop strategies to mitigate these risks.
Check Digit Verification of cas no
The CAS Registry Mumber 122457-31-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,4,5 and 7 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 122457-31:
(8*1)+(7*2)+(6*2)+(5*4)+(4*5)+(3*7)+(2*3)+(1*1)=102
102 % 10 = 2
So 122457-31-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H11N5/c1-6-5-13-7-3-4-8-10(9(7)14-6)15-11(12)16(8)2/h3-5H,1-2H3,(H2,12,15)/i2D3
122457-31-2Relevant articles and documents
Synthesis of the Food Mutagens MeIQx and 4,8-DiMeIQx by Copper(I) Promoted Quinoxaline Formation
Knapp, Spencer,Ziv, Joseph,Rosen, Joseph D.
, p. 1293 - 1298 (2007/10/02)
The regiocontrolled syntheses of the title compounds (1 and 2) is described.The key step is a new intramolecular alkyne amination and aromatization process (5 6; 8 9) effected by tetrakis(acetonitrile)copper(I) tetrafluoroborate.
