1224949-36-3

Basic information

• Product Name: 3-(8-hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)-1-(p-tolyl)-2-propyn-1-one
• Synonyms: 3-(8-hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)-1-(p-tolyl)-2-propyn-1-one
• CAS NO: 1224949-36-3
• Molecular Weight: 300.354
• Mol File: 1224949-36-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(8-hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)-1-(p-tolyl)-2-propyn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(8-hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)-1-(p-tolyl)-2-propyn-1-one(1224949-36-3)
• EPA Substance Registry System: 3-(8-hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)-1-(p-tolyl)-2-propyn-1-one(1224949-36-3)

Safety Data

• Hazardous Substances Data: 1224949-36-3(Hazardous Substances Data)

Upstream product

• 320342-34-5 8-[(trimethylsilyl)ethynyl]-1,4-dioxaspiro[4.5]decan-8-ol 
• 1224949-24-9 8-(3-hydroxy-3-(p-tolyl)propyn-1-yl)-1,4-dioxaspiro[4.5]decan-8-ol 
• 4746-97-8 cyclohexanedione monoethylene ketal 

Downstream Products

• 1224949-55-6 8-(1-(4-chlorophenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-1,4-dioxaspiro[4.5]decan-8-ol 
• 1224949-51-2 8-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-1,4-dioxaspiro[4.5]decan-8-ol 
• 1224948-64-4 c-4-hydroxy-4-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-cyclohexan-r-1-yl acetate 
• 1224948-65-5 4-(4-chloro-1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-c-4-hydroxy-cyclohexan-r-1-yl acetate 
• 1224948-67-7 t-4-fluoro-4-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-cyclohexan-r-1-ol 
• 1224948-44-0 4-hydroxy-4-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-cyclohexan-1-one 
• 1224948-68-8 4,4-difluoro-1-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)cyclohexanol 
• 1224950-00-8 c-4-methoxy-1-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-cyclohexan-r-1-yl acetate 
• 1224950-01-9 4-(4-fluoro-1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-c-4-hydroxy-cyclohexan-r-1-yl acetate 
• 1224950-02-0 1-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-4-oxo-cyclohexan-1-yl acetate 
• 1224949-08-9 c-4-hydroxy-1-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-cyclohexan-r-1-yl acetate 
• 1224950-03-1 4-hydroxy-4-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)-cis-cyclohexane-1-carbaldehyde 
• 1224948-05-3 1-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)cyclohexan-trans-1,4-diol 
• 1224948-70-2 4-methoxy-1-(1-(4-methoxyphenyl)-5-(p-tolyl)-1H-pyrazol-3-yl)cyclohexanol 

Relevant articles and documents

THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR FIBROMYALGIA

An object of the present invention is to provide a therapeutic agent or prophylactic agent which has an analgesic effect on both nociceptive pain and neuropathic pain and is effective in treatment of fibromyalgia. The present invention provides a therapeutic agent or prophylactic agent for fibromyalgia, said agent comprising as an effective ingredient a cyclohexane derivative exemplified by the formula below, or a pharmaceutically acceptable salt thereof or a prodrug thereof.

CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

The present invention aims to provide a compound having a strong analgesic action against both nociceptive pain and neuropathic pain and having less side effects, and a medical use thereof. The present invention provides cyclohexane derivatives represented by the following compound, or pharmaceutically acceptable salts thereof or prodrugs thereof.