122706-39-2

Basic information

• Product Name: 2-Hydroxymethyl-N-phenyl-nicotinamide
• Synonyms: 2-Hydroxymethyl-N-phenyl-nicotinamide
• CAS NO: 122706-39-2
• Molecular Weight: 228.25
• Mol File: 122706-39-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Hydroxymethyl-N-phenyl-nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxymethyl-N-phenyl-nicotinamide(122706-39-2)
• EPA Substance Registry System: 2-Hydroxymethyl-N-phenyl-nicotinamide(122706-39-2)

Safety Data

• Hazardous Substances Data: 122706-39-2(Hazardous Substances Data)

Upstream product

• 6538-81-4 6-Phenylpyrrolo<3,4-b>pyridine-5,7(6H)-dione 
• 122706-33-6 6,7-dihydro-7-hydroxy-6-phenyl-5H-pyrrolo<3,4-b>pyridin-5-one 

Downstream Products

• 5657-51-2 7H-furo[3,4-b]pyridin-5-one 

Relevant articles and documents

Regioselective Formation of Hydroxy Lactams from Pyridine-2,3-dicarboximides and their Cyclodehydration to Pyridopyrrolo-fused Heterocyclic Systems

Grignard reactions of pyridine-2,3-dicarboximides involve attack at the carbonyl group closer to the pyridine nitrogen atom to give 7-hydroxypyrrolopyridin-5(7H)-one derivatives.Reduction of the same imides with sodium borohydride gives mixtures of regiosomeric hydroxy lactams, in which the 7-hydroxypyrrolopyridin-5-ones are the major components.Hydroxy lactams derived by either of these two methods from pyridine-2,3-dicarboximides containing N-benzyl, N-2-phenylethyl, N-2-(indol-3-yl)ethyl, or N-biphenyl-2-yl substituents are cyclised by heating in trifluoroacetic or polyphosphoric acid to give derivatives of new pyridopyrrolo-fused heterocyclic systems.