1227062-96-5

Basic information

• Product Name: (R)-N⁽¹⁾-benzyl-2-allylpiperidine
• Synonyms: (R)-N⁽¹⁾-benzyl-2-allylpiperidine
• CAS NO: 1227062-96-5
• Molecular Weight: 215.338
• Mol File: 1227062-96-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-N⁽¹⁾-benzyl-2-allylpiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N⁽¹⁾-benzyl-2-allylpiperidine(1227062-96-5)
• EPA Substance Registry System: (R)-N⁽¹⁾-benzyl-2-allylpiperidine(1227062-96-5)

Safety Data

• Hazardous Substances Data: 1227062-96-5(Hazardous Substances Data)

Upstream product

• 55162-83-9 4-formylbutyl benzoate 
• 55162-82-8 1-benzoyloxypentan-5-ol 
• 111-29-5 1 ,5-pentanediol 
• 100-46-9 benzylamine 
• 14429-03-9 (R)-N-benzyl-N-(α-methyl-p-methoxybenzyl)amine 
• 100-52-7 benzaldehyde 
• 117471-84-8 1,1-dimethylethyl (E)-7-hydroxyhept-2-enoate 
• 881830-03-1 (R)-2-[N⁽¹⁾-benzylpiperidin-2-yl]ethanol 
• 1227062-94-3 tert-butyl (3R,αR)-3-[N-benzyl-N-(α-methyl-p-methoxybenzyl)amino]-7-iodoheptanoate 
• 1227062-93-2 tert-butyl (R,R)-3-[N-benzyl-N-(α-methyl-p-methoxybenzyl)amino]-7-hydroxyheptanoate 
• 1227062-91-0 tert-butyl (R)-2-[N⁽¹⁾-benzylpiperidin-2-yl]acetate 
• 1227062-90-9 tert-butyl (R,R)-3-[N-benzyl-N-(α-methylbenzyl)amino]-7-iodoheptanoate 
• 1227062-89-6 tert-butyl (R,R)-3-[N-benzyl-N-(α-methylbenzyl)amino]-7-hydroxyheptanoate 
• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 

Downstream Products

• 555-92-0 (S)-coniine hydrochloride 
• 458-88-8 coniine 

Relevant articles and documents

Bisnucleophilic substitution as a synthetic tool for ready access to the piperidine alkaloids (+)-Connine, (+)-β-conhydrine, (+)-8-ethylnorlobelol, and (-)-halosaline

Herein we report the stereoselective total synthesis of (+)-connine, (+)-β-conhydrine, (+)-8-ethylnorlobelol, and (-)-halosaline via bisnucleophilic substitution with benzylamine as the key step.

Asymmetric synthesis of piperidines and octahydroindolizines

The conjugate addition of a homochiral lithium amide to a ξ-hydroxy-α,β-unsaturated ester, followed by a one-pot, ring-closure-N-debenzylation protocol has been used in the asymmetric syntheses of (S)-coniine and (R)-δ-coniceine (isolated as the corresponding hydrochloride salts) and the bicyclic core of stellettamide A. Georg Thieme Verlag Stuttgart.