1227781-74-9Relevant articles and documents
Direct synthesis of trisubstituted isoxazoles through gold-catalyzed domino reaction of alkynyl oxime ethers
Ueda, Masafumi,Sato, Aoi,Ikeda, Yuki,Miyoshi, Tetsuya,Naito, Takeaki,Miyata, Okiko
supporting information; experimental part, p. 2594 - 2597 (2010/08/07)
Alkynyl oxime ether underwent a gold-catalyzed domino reaction involving cyclization and subsequent Claisen-type rearrangement to afford trisubstituted isoxazoles in a direct, efficient, and regioselective manner. The products were successfully applied to the synthesis of unusual heterocycles as an illustration of the potential utility of the reaction.