1228187-44-7

Basic information

• Product Name: tert-butyl 4-(4'-methylbiphenyl-4-yl)piperazine-1-carboxylate
• Synonyms: tert-butyl 4-(4'-methylbiphenyl-4-yl)piperazine-1-carboxylate
• CAS NO: 1228187-44-7
• Molecular Weight: 352.477
• Mol File: 1228187-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(4'-methylbiphenyl-4-yl)piperazine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(4'-methylbiphenyl-4-yl)piperazine-1-carboxylate(1228187-44-7)
• EPA Substance Registry System: tert-butyl 4-(4'-methylbiphenyl-4-yl)piperazine-1-carboxylate(1228187-44-7)

Safety Data

• Hazardous Substances Data: 1228187-44-7(Hazardous Substances Data)

Upstream product

• 4294-57-9 para-methylphenylmagnesium bromide 
• 352437-09-3 tert-butyl 4-(4-bromophenyl)piperazine-1-carboxylate 

Relevant articles and documents

Efficient synthesis of biaryls through the kumada reaction catalyzed by carbene adducts of cyclopalladated ferrocenylimine

A series of carbene adducts of cyclopalladated ferrocenylimine were prepared, and evaluated in the cross-coupling reaction of aryl halides with Grignard reagents (the Kumada reaction). Complex d exhibited high catalytic activity for the coupling of aryl chlorides with sterically hindered Grignard reagents and the reaction tolerated various functional groups. A wide range of biaryls were efficiently obtained in good to excellent yields in the presence of 0.5 mol-% catalyst under mild reaction conditions.