123117-63-5

Basic information

• Product Name: 4-Thiazolepentanamine, N-(3,4-dihydro-2H-pyrrol-5-yl)-2-(ethylamino)-5-(4-nitrophenyl)-, monohydrobromide
• CAS NO: 123117-63-5
• Molecular Formula: C20H27N5O2S.BrH
• Molecular Weight: 482.445
• Mol File: 123117-63-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Thiazolepentanamine, N-(3,4-dihydro-2H-pyrrol-5-yl)-2-(ethylamino)-5-(4-nitrophenyl)-, monohydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolepentanamine, N-(3,4-dihydro-2H-pyrrol-5-yl)-2-(ethylamino)-5-(4-nitrophenyl)-, monohydrobromide(123117-63-5)
• EPA Substance Registry System: 4-Thiazolepentanamine, N-(3,4-dihydro-2H-pyrrol-5-yl)-2-(ethylamino)-5-(4-nitrophenyl)-, monohydrobromide(123117-63-5)

Safety Data

• Hazardous Substances Data: 123117-63-5(Hazardous Substances Data)

Upstream product

• 5264-35-7 2-methoxy-1-pyrroline 
• 143602-41-9 Ethyl-[4-(5-methylamino-pentyl)-5-(4-nitro-phenyl)-thiazol-2-yl]-amine; hydrobromide 
• 143602-53-3 1-Ethyl-2-(4-nitro-benzyl)-isothiourea; hydrobromide 
• 33324-50-4 2,2-diethoxyhexahydro-1-methyl-1H-azepine 

Relevant articles and documents

Synthesis of 4-(ω-aminoalkyl)- or 4-(ω-lactamiminoalkyl)thiazoles by ring chain transformation of isothioureas with lactam derivatives

CH-Acidic isothioureas 1 react with lactam acetals 2 at the unsubstituted N-atom as well as at the acidic S-methylene group giving 4-(ω-aminoalkyl)thiazoles 6. The latter are further transformed to 4-(ω-lactamiminoalkyl)thiazoles 8, if lactim ethers 3 are used in reactions with isothioureas 1.