1232144-64-7Relevant articles and documents
Synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity
Dao, Pascal,Jarray, Rafika,Le Coq, Johanne,Lietha, Daniel,Loukaci, Ali,Lepelletier, Yves,Hadj-Slimane, Réda,Garbay, Christiane,Raynaud, Fran?oise,Chen, Huixiong
, p. 4552 - 4556 (2013/08/23)
We report herein the synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK (focal adhesion kinase) inhibitors and the evaluation of their anti-angiogenic activity on HUVEC cells. Generally, the effects of these compounds on endothelial cells co
High yielding microwave-assisted synthesis of 2-(arylmethyl)amino-4-arylamino-6-alkyl-1,3,5-triazines
Chen, Huixiong,Dao, Pascal,Laporte, Alice,Garbay, Christiane
experimental part, p. 3174 - 3176 (2010/08/05)
An efficient and practical procedure was developed to prepare novel 2-(arylmethyl)amino-4-arylamino-6-alkyl-1,3,5-triazines, starting from dicyandiamide and the corresponding arylamines under microwave irradiation and its scope is demonstrated with a number of examples. The valuable feature of this procedure included the short reaction times, high yields, and easy operation.