123228-27-3Relevant articles and documents
Stereochemical aspects in the synthesis of novel N-(purin-6-yl)dipeptides as potential antimycobacterial agents
Musiyak, Vera V.,Nizova, Irina A.,Chulakov, Evgeny N.,Sadretdinova, Liliya Sh.,Tumashov, Andrey A.,Levit, Galina L.,Krasnov, Victor P.
, p. 407 - 415 (2021/02/26)
The synthesis of purine conjugates with natural amino acids is one of the promising directions in search for novel therapeutic agents, including antimycobacterial agents. The purpose of this study was to synthesize N-(purin-6-yl)dipeptides containing the
CLEAVAGE OF PEPTIDE TO SPARROW-RESIN BOND BY CATALYTIC TRANSFER HYDROGENOLYSIS WITH 1,4-CYCLOHEXADIENE
Colombo, Roberto
, p. 1119 - 1122 (2007/10/02)
Cleavage of benzyl ester-type linkage to the Sparrow modified polystyrene support was attempted with the aid of catalytic transfer hydrogenation using 1,4-cyclohexadiene and palladium black, and satisfactory yields were obtained.This will provide an alternatively efficient and mild method for the final deblocking step during improved solid phase peptide synthesis.