123290-35-7Relevant articles and documents
Synthesis of 3-substituted 2-cyclohexenones through umpoled functionalization
Lechuga-Eduardo, Harim,Zarza-Acu?a, Eduardo,Romero-Ortega, Moisés
, p. 3234 - 3237 (2017/07/27)
A new protocol to obtain 3-substituted 2-cyclohexenones, was developed by reversing the chemical reactivity of 2-cyclohexenone. One-pot synthesis of 3-substituted 2-cyclohexenones can be achieved by treatment of 3-phenylthiosilyl enol ether with a mixture of t-BuLi/HMPA that allows hydrogen-selective exchange in presence of reactive electrophiles such as aldehydes, ketones and alkyl halides. This affords the corresponding product in moderate overall yield, after silyl enol ether cleavage and concomitant thiophenol elimination initiated with TBAF.
Synthesis of an epoxyquinol analog: Efficient methodology for the insertion of side chains into cyclohexenone cores
Heguaburu, Viviana,Schapiro, Valeria,Pandolfi, Enrique
scheme or table, p. 6921 - 6923 (2011/02/27)
A novel epoxyquinol analog was prepared by molecular simplification of monomeric and dimeric scaffolds. A feasible methodology for the insertion of side chains into cyclohexenone skeleton was developed. Insertion of the hydroxymethyl side chain was achiev
Nucleophilic Reactivity of Zinc and Copper Carbenoids. 2
Knochel, Paul,Chou, Tso-Sheng,Chen, Huai Gu,Yeh, Ming Chang P.,Rozema, Michael J.
, p. 5202 - 5204 (2007/10/02)
The rectivity of the new zinc and copper carbenoids PivOCH2Cu(CN)ZnI (4) and ICH2Cu*ZnI2 (5) toward various electrophiles has been investigated.Of special interest is the direct and highly stereoselective conversion of allylic bromides to the corresponding homoallylic iodides by using the reagent ICH2Cu*ZnI2
