1234479-76-5 Usage
Uses
ERK5-IN-1 is a potent selective ERK5 inhibitor, inhibiting EGFR-induced ERK5 autophosphorylation and ERK5 enzymatic activity. Orally bioavailable.
Check Digit Verification of cas no
The CAS Registry Mumber 1234479-76-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,4,4,7 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1234479-76:
(9*1)+(8*2)+(7*3)+(6*4)+(5*4)+(4*7)+(3*9)+(2*7)+(1*6)=165
165 % 10 = 5
So 1234479-76-5 is a valid CAS Registry Number.
1234479-76-5Relevant articles and documents
Discovery of a benzo[e]pyrimido-[5,4-b][1,4]diazepin-6(11H)-one as a potent and selective inhibitor of big MAP kinase 1
Deng, Xianming,Yang, Qingkai,Kwiatkowski, Nicholas,Sim, Taebo,McDermott, Ultan,Settleman, Jeffrey E.,Lee, Jiing-Dwan,Gray, Nathanael S.
, p. 195 - 200 (2011/05/03)
Kinome-wide selectivity profiling of a collection of 2-amino-pyrido[2,3-d] pyrimidines followed by cellular structure-activity relationship-guided optimization resulted in the identification of moderately potent and selective inhibitors of BMK1/ERK5 exemp
