1234616-67-1 Usage
Description
1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile is a heterocyclic compound characterized by its unique chemical structure, which consists of a pyrazolo and pyridine ring fused together. 1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile is known for its potential applications in various fields due to its chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile is used as a key intermediate compound for the synthesis of novel bifunctional compounds, specifically IRAK degraders. These degraders are designed to modulate the activity of IRAK proteins, which play a crucial role in the regulation of immune responses. By targeting IRAK proteins, these bifunctional compounds have the potential to be developed into therapeutic agents for the treatment of various inflammatory and autoimmune diseases.
Additionally, due to its unique chemical structure, 1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile may also be utilized in the development of other pharmaceutical compounds with diverse applications, such as antiviral, anticancer, or anti-inflammatory agents. Its versatility in chemical reactions allows for the creation of a wide range of derivatives with potential therapeutic properties.
Used in Chemical Research:
1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile serves as a valuable research tool for chemists and material scientists. Its unique structure and reactivity make it an interesting candidate for studying various chemical reactions and mechanisms. 1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile can be used to explore new synthetic routes, develop novel catalysts, or investigate the properties of related heterocyclic systems.
Check Digit Verification of cas no
The CAS Registry Mumber 1234616-67-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,4,6,1 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1234616-67:
(9*1)+(8*2)+(7*3)+(6*4)+(5*6)+(4*1)+(3*6)+(2*6)+(1*7)=141
141 % 10 = 1
So 1234616-67-1 is a valid CAS Registry Number.
1234616-67-1Relevant articles and documents
IRAK DEGRADERS AND USES THEREOF
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Paragraph 00962; 003058-003060, (2020/06/19)
The present invention provides compounds, compositions thereof, and methods of using the same.
Zinc Acetate-Promoted Buchwald-Hartwig Couplings of Heteroaromatic Amines
Ayothiraman, Rajaram,Rangaswamy, Sundaramurthy,Maity, Prantik,Simmons, Eric M.,Beutner, Gregory L.,Janey, Jacob,Treitler, Daniel S.,Eastgate, Martin D.,Vaidyanathan, Rajappa
, p. 7420 - 7427 (2017/07/26)
Zinc salts have been shown to promote the Buchwald-Hartwig coupling of azaindoles and azaindazoles with heteroaryl chlorides to provide the corresponding 1-aryl-1H-azaindoles and 1-aryl-1H-azaindazoles. The substrate scope and mechanistic aspects of this reaction were explored.
