123532-25-2

Basic information

• Product Name: 2-(2-Methyl-2H-pyrazol-3-yl)-4-nitrophenol
• Synonyms: 2-(2-Methyl-2H-pyrazol-3-yl)-4-nitrophenol
• CAS NO: 123532-25-2
• Molecular Formula: C₁₀H₉N₃O₃
• Molecular Weight: 219.19676
• Mol File: 123532-25-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-Methyl-2H-pyrazol-3-yl)-4-nitrophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Methyl-2H-pyrazol-3-yl)-4-nitrophenol(123532-25-2)
• EPA Substance Registry System: 2-(2-Methyl-2H-pyrazol-3-yl)-4-nitrophenol(123532-25-2)

Safety Data

• Hazardous Substances Data: 123532-25-2(Hazardous Substances Data)

Usage

Physical state

Yellow crystalline solid

Uses

Widely used in pharmaceutical and agricultural industries

Functions

Intermediate in organic synthesis, pharmaceutical intermediate, agrochemical intermediate

Known for

Inhibiting various enzymes, precursor for synthesis of other organic compounds

Potential pharmacological properties

Anti-inflammatory and antioxidant effects

Upstream product

• 51484-05-0 6-nitro-chromen-4-one 
• 60-34-4 methylhydrazine 
• 720702-43-2 5-(2-methoxy-5-nitro-phenyl)-1-methyl-1H-pyrazole 

Downstream Products

• 887937-81-7 2-[2-(2-methyl-2H-pyrazol-3-yl)-4-nitro-phenoxymethyl]-pyridine 
• 887938-10-5 4-{2-[2-(2-methyl-2H-pyrazol-3-yl)-4-nitro-phenoxy]-ethyl}morpholine 
• 839713-67-6 5-(2-isopropoxy-5-nitrophenyl)-1-methyl-1H-pyrazole 
• 839713-62-1 5-(2-ethoxy-5-nitrophenyl)-1-methyl-1H-pyrazole 
• 839713-75-6 5-(2-benzyloxy-5-nitrophenyl)-1-methyl-1H-pyrazole 
• 839713-86-9 1-methyl-5-(5-nitro-2-phenethyloxyphenyl)-1H-pyrazole 
• 839713-81-4 5-[2-(4-chlorobenzyloxy)-5-nitrophenyl]-1-methyl-1H-pyrazole 
• 887937-64-6 5-[2-(2-bromo-ethoxy)-5-nitro-phenyl]-1-methyl-1H-pyrazole 

Relevant articles and documents

Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1 H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A highly selective 5-hydroxytryptamine2A receptor inverse agonist for the treatment of arterial thrombo

Serotonin, which is stored in platelets and is released during thrombosis, activates platelets via the 5-HT2A receptor. 5-HT2A receptor inverse agonists thus represent a potential new class of antithrombotic agents. Our medicinal pro

DIARYL AND ARYLHETEROARYL UREA DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERTO

The present invention relates to certain pyrazole derivatives of Formula (I) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to