1235976-71-2

Basic information

• Product Name: (R)-diethyl 3-((2-(3,4-dihydroxyphenyl)-2-hydroxyethyl)methylamino)prop-1-en-2-ylphosphonate
• Synonyms: (R)-diethyl 3-((2-(3,4-dihydroxyphenyl)-2-hydroxyethyl)methylamino)prop-1-en-2-ylphosphonate
• CAS NO: 1235976-71-2
• Molecular Weight: 359.359
• Mol File: 1235976-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-diethyl 3-((2-(3,4-dihydroxyphenyl)-2-hydroxyethyl)methylamino)prop-1-en-2-ylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-diethyl 3-((2-(3,4-dihydroxyphenyl)-2-hydroxyethyl)methylamino)prop-1-en-2-ylphosphonate(1235976-71-2)
• EPA Substance Registry System: (R)-diethyl 3-((2-(3,4-dihydroxyphenyl)-2-hydroxyethyl)methylamino)prop-1-en-2-ylphosphonate(1235976-71-2)

Safety Data

• Hazardous Substances Data: 1235976-71-2(Hazardous Substances Data)

Upstream product

• 1235976-42-7 diethyl (α-acetoxymethyl)vinylphosphonate 
• 51-43-4 L-epinephrine 

Relevant articles and documents

Synthesis of β-aminovinylphosphonates by organocatalytic nucleophilic displacement of acetate with amines

The synthesis of diethyl β-aminovinylphosphonates 2 from acetoxy phosphonate 1 is described. The reaction entails an organocatalyzed substitution of the acetoxy group by primary or secondary amines. The use of a catalytic amount of DABCO is necessary if the amine is not nucleophilic enough, otherwise a strong nucleophilic amine can react without organocatalyst. The reaction led to a series of functionalized title compounds in good to excellent yields.