1236109-29-7

Basic information

• Product Name: (Z)-7-[(1R,2R,3R)-2-((E)-4,4-difluoro-3-oxo-1-octenyl)-3-(phenylmethoxy)-5-oxocyclopentyl]-5-heptenoic acid
• Synonyms: (Z)-7-[(1R,2R,3R)-2-((E)-4,4-difluoro-3-oxo-1-octenyl)-3-(phenylmethoxy)-5-oxocyclopentyl]-5-heptenoic acid
• CAS NO: 1236109-29-7
• Molecular Weight: 476.561
• Mol File: 1236109-29-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-7-[(1R,2R,3R)-2-((E)-4,4-difluoro-3-oxo-1-octenyl)-3-(phenylmethoxy)-5-oxocyclopentyl]-5-heptenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-7-[(1R,2R,3R)-2-((E)-4,4-difluoro-3-oxo-1-octenyl)-3-(phenylmethoxy)-5-oxocyclopentyl]-5-heptenoic acid(1236109-29-7)
• EPA Substance Registry System: (Z)-7-[(1R,2R,3R)-2-((E)-4,4-difluoro-3-oxo-1-octenyl)-3-(phenylmethoxy)-5-oxocyclopentyl]-5-heptenoic acid(1236109-29-7)

Safety Data

• Hazardous Substances Data: 1236109-29-7(Hazardous Substances Data)

Upstream product

• 50889-46-8 dimethyl (3,3-difluoro-2-oxoheptyl)-phosphonate 
• 1424864-71-0 (5Z)-7-[(1R,2R,3R)-3-(benzyloxy)-2-formyl-5-oxocyclopentyl]hept-5-enoic acid 
• 1236109-28-6 (Z)-7-[(1R,2R,3R,5S)-2-((E)-4,4-difluoro-3-hydroxy-1-octenyl)-3-(phenylmethoxy)-5-hydroxycyclopentyl]-5-heptenoic acid 
• 1236109-27-5 (3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-hydroxy-1-octenyl)-5-(phenylmethoxy)-hexahydro-2H-cyclopenta[b]furan-2-ol 
• 81190-06-9 [(3aR,4S,5R,6aS)-hexahydro-4-(hydroxymethyl)-5-(phenylmethoxy)-2H-cyclopenta[b]furan-2-one] 
• 1236109-25-3 (3aR,4S,5R,6aS)-5-(benzyloxy)-4-(((triisopropylsilyl)oxy)methyl)hexahydro-2H-cyclopenta[b]furan-2-one 
• 1236109-24-2 [(3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4(triisopropylsilyloxymethyl)-2H-cyclopenta[b]furan-2-one] 
• 32233-40-2 (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one 
• 163074-98-4 [(3aR,4R,5R,6aS)-hexahydro-2-oxo-5-(phenylmethoxy)-2H-cyclopenta[b]furan-4-carboxaldehyde] 
• 1236109-50-4 benzyl (Z)-7-[(1R,2R,3R,5S)-2-((E)-4,4-difluoro-3-hydroxy-1-octenyl)-3-(phenylmethoxy)-5-hydroxycyclopentyl]-5-heptenoate 

Downstream Products

• 136790-76-6 13,14-dihydro-15-keto-16,16-difluoro-Prostaglandin E₁ 

Relevant articles and documents

DIMETHYL-(3,3-DIFLUORO-2,2-DIHYDROXYHEPTYL)PHOSPHONATE AND PROCESSES FOR ITS PREPARATION

A compound dimethyl-(3,3-difluoro-2,2-dihydroxyheptyl)phosphonate (I), a crystalline form of this compound, processes for its preparation, and use of this compound in the preparation of prostaglandin derivatives such as Lubiprostone.

METHODS OF MAKING LUBIPROSTONE AND INTERMEDIATES THEREOF

There is provided processes for preparing Lubiprostone and intermediates thereof. Also provided are compounds, including intermediates for preparing Lubiprostone as well as compositions comprising Lubiprostone and other compounds, including intermediates for preparing Lubiprostone and other compounds. (I)