1236130-79-2

Basic information

• Product Name: 2-{3-[(5-chloro-4-{[2-(3-methoxyphenyl)ethyl]amino}pyrimidin-2-yl)amino]phenyl}ethanol
• Synonyms: 2-{3-[(5-chloro-4-{[2-(3-methoxyphenyl)ethyl]amino}pyrimidin-2-yl)amino]phenyl}ethanol
• CAS NO: 1236130-79-2
• Molecular Weight: 398.892
• Mol File: 1236130-79-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{3-[(5-chloro-4-{[2-(3-methoxyphenyl)ethyl]amino}pyrimidin-2-yl)amino]phenyl}ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{3-[(5-chloro-4-{[2-(3-methoxyphenyl)ethyl]amino}pyrimidin-2-yl)amino]phenyl}ethanol(1236130-79-2)
• EPA Substance Registry System: 2-{3-[(5-chloro-4-{[2-(3-methoxyphenyl)ethyl]amino}pyrimidin-2-yl)amino]phenyl}ethanol(1236130-79-2)

Safety Data

• Hazardous Substances Data: 1236130-79-2(Hazardous Substances Data)

Upstream product

• 1236130-76-9 2,5-dichloro-N-[2-(3-methoxyphenyl)ethyl]pyrimidin-4-amine 
• 52273-77-5 2-(3-aminophenyl)ethan-1-ol 

Downstream Products

• 1236130-80-5 3-{2-[(2-{[3-(2-bromoethyl)phenyl]amino}-5-chloropyrimidin-4-yl)amino]ethyl}phenol 

Relevant articles and documents

MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS

The present invention relates to macrocyclic compounds of Formula I: or pharmaceutically acceptable salts thereof or quaternary ammonium salts thereof wherein constituent members are provided hereinwith, as well as their compositions and methods of use, which are JAK/ALK inhibitors useful in the treatment of JAK/ALK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer.