1236142-07-6

Basic information

• Product Name: Boc-Pro-Pro-Ile-OBzl
• CAS NO: 1236142-07-6
• Molecular Weight: 515.65
• Mol File: 1236142-07-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Boc-Pro-Pro-Ile-OBzl(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Pro-Pro-Ile-OBzl(1236142-07-6)
• EPA Substance Registry System: Boc-Pro-Pro-Ile-OBzl(1236142-07-6)

Safety Data

• Hazardous Substances Data: 1236142-07-6(Hazardous Substances Data)

Upstream product

• 731779-67-2 TFA*Pro-Ile-OBzl 
• 883565-15-9 C₁₅H₂₅NO₅ 

Relevant articles and documents

Synthesis of Pro-Pro-Ile, a corticoliberin fragment, labeled with tritium in proline unit

Boc-δ3Pro-Pro-Ile-OBzl and Boc-Pro-δ3Pro- Ile-OBzl were synthesized. Tritium-labeled Pro-Pro-Ile was prepared by their hydrogenation in a tritium atmosphere in the presence of a catalyst. In the reduction of Boc-δ3Pro-Pro-Ile-OBzl and Boc-Pro- δ3Pro-Ile-OBzl, elimination of the Bzl protective group occurs faster than hydrogenation of the 3,4-dehydroproline residue (benzene and dioxane were used as solvents). The resulting Boc-δ3Pro-Pro-Ile-OH and Boc-Pro-δ3Pro-Ile-OH are poorly soluble in aprotic solvents, which accounts for the low yield of the desired tritium-labeled peptides. Pleiades Publishing, Inc., 2010.