123622-36-6 Usage
Description
FMOC-GLU(OBZL)-CL, also known as 9-fluorenylmethoxycarbonyl-L-glutamic acid (2-benzyloxy-4-methylphenyl)methyl ester hydrochloride, is a chemical compound used in the synthesis of peptidomimetics. It is a protected amino acid derivative that plays a crucial role in the solid-phase synthesis of these bioactive molecules.
Uses
Used in Pharmaceutical Industry:
FMOC-GLU(OBZL)-CL is used as a reactant in the solid-phase synthesis of oxazole-containing peptidomimetics for their potential therapeutic applications. These peptidomimetics are designed to mimic the structure and function of natural peptides, offering improved stability, bioavailability, and target specificity. The incorporation of oxazole rings in these molecules can lead to enhanced biological activity and selectivity, making them valuable candidates for drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 123622-36-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,6,2 and 2 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 123622-36:
(8*1)+(7*2)+(6*3)+(5*6)+(4*2)+(3*2)+(2*3)+(1*6)=96
96 % 10 = 6
So 123622-36-6 is a valid CAS Registry Number.
123622-36-6Relevant articles and documents
Rapid Continous Peptide Synthesis via FMOC Amino Acid Chloride Coupling and 4-(Aminomethyl)piperidine Deblocking
Beyermann, Michael,Bienert, Michael,Niedrich, Hartmut,Carpino, Louis A.,Sadat-Aalaee, Dean
, p. 721 - 728 (2007/10/02)
The recently described FMOC/4-AMP technique for rapid continous solution synthesis of peptides involving coupling by crystalline FMOC amino acid chlorides and deblocking via 4-(aminomethyl)piperidine (4-AMP) has been extended to the synthesis of a varied
