1236352-67-2Relevant articles and documents
Metal-free synthesis of polysubstituted pyrroles by (diacetoxyiodo)benzene- mediated cascade reaction of 3-alkynyl amines
Mo, Dong-Liang,Ding, Chang-Hua,Dai, Li-Xin,Hou, Xue-Long
supporting information, p. 3200 - 3204 (2013/01/12)
Free metal jacket: A regioselective metal-free synthesis of polysubstituted pyrroles has been developed through a (diacetoxyiodo)benzene-mediated cascade reaction of alkynyl amines in moderate to good yield (see scheme).
Gold-catalyzed synthesis of α-fluoro acetals and α-fluoro ketones from alkynes
De Haro, Teresa,Nevado, Cristina
supporting information; experimental part, p. 2767 - 2772 (2010/12/25)
A new method to synthesize α-fluoro acetals and α-fluoro ketones is presented here. In the presence of alcohols and Selectfluor, catalytic amounts of gold selectively transformed alkynes into the corresponding fluorinated acetals or ketones depending on the reaction conditions. This protocol has been applied to both terminal and internal alkynes showing a high degree of chemo- and regioselectivity. The reaction mechanism seems to proceed via two co-existing pathways, since at least partially, the formation of the C(sp3)-F bond in the final products occurs at the metal center.
