1239600-18-0 Usage
General Description
The chemical "(R)-3-((2R,3R)-3-hydroxy-2-methyl-4-methylenenonanoyl)-4-isopropyloxazolidin-2-one" is a complex compound with a long and intricate name. It belongs to the class of oxazolidinones and contains a hydroxy and a isopropyl group. The molecule has a chirality center, denoted by the "(R)" prefix, and consists of a nonanoic acid derivative connected to an oxazolidinone ring. This chemical may have potential uses in pharmaceuticals, as oxazolidinones are known for their antibacterial properties and are used in the treatment of various infections. The specific structure and properties of this compound make it a subject of interest for further research and potential applications in the field of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 1239600-18-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,9,6,0 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1239600-18:
(9*1)+(8*2)+(7*3)+(6*9)+(5*6)+(4*0)+(3*0)+(2*1)+(1*8)=140
140 % 10 = 0
So 1239600-18-0 is a valid CAS Registry Number.
1239600-18-0Relevant articles and documents
Structure-activity relationship study of a series of novel oxazolidinone derivatives as IL-6 signaling blockers
Singh, Sarbjit,Gajulapati, Veeraswamy,Gajulapati, Kondaji,Goo, Ja-Il,Park, Yeon-Hwa,Jung, Hwa Young,Lee, Sung Yoon,Choi, Jung Ho,Kim, Young Kook,Lee, Kyeong,Heo, Tae-Hwe,Choi, Yongseok
, p. 1282 - 1286 (2016)
A series of oxazolidinone and indole derivatives were synthesized and evaluated as IL-6 signaling blockers by measuring the effects of these compounds on IL-6-induced luciferase expression in human hepatocarcinoma HepG2 cells transfected with p-STAT3-Luc. Among different compounds screened, compound 4d was emerged as the most potent IL-6 signaling blockers with IC50 value of 5.9 μM which was much better than (+)-Madindoline A (IC50 = 21 μM), a known inhibitor of IL-6.
