1239664-46-0

Basic information

• Product Name: (R)-4-benzyl-3-[(S)-2-(tert-butyldimethylsilyloxymethyl)butanoyl]oxazolidin-2-one
• Synonyms: (R)-4-benzyl-3-[(S)-2-(tert-butyldimethylsilyloxymethyl)butanoyl]oxazolidin-2-one
• CAS NO: 1239664-46-0
• Molecular Weight: 391.583
• Mol File: 1239664-46-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-4-benzyl-3-[(S)-2-(tert-butyldimethylsilyloxymethyl)butanoyl]oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-benzyl-3-[(S)-2-(tert-butyldimethylsilyloxymethyl)butanoyl]oxazolidin-2-one(1239664-46-0)
• EPA Substance Registry System: (R)-4-benzyl-3-[(S)-2-(tert-butyldimethylsilyloxymethyl)butanoyl]oxazolidin-2-one(1239664-46-0)

Safety Data

• Hazardous Substances Data: 1239664-46-0(Hazardous Substances Data)

Upstream product

• 645386-89-6 (R)-4-benzyl-3-((S)-2-(benzyloxymethyl)butanoyl)-1,3-oxazolidin-2-one 
• 111292-87-6 (R)-3-(1-butyryl)-4-benzyloxazolidine-2-one 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 907593-86-6 (R)-4-benzyl-3-[(S)-2-(hydroxymethyl)butanoyl]oxazolidin-2-one 

Downstream Products

• 339533-74-3 (R)-2-((tert-butyldimethylsilyloxy)methyl)butan-1-ol 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 101711-78-8 (3R)-3-propionyl-4-benzyloxazolidin-2-one 
• 1501971-58-9 (4R)-4-benzyl-3-((2R,3S,4R)-3-hydroxy-2,4-dimethylhexanoyl)oxazolidin-2-one 
• 1501971-59-0 (2R,3S,4R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-2,4-dimethyl-1-oxohexan-3-yl-4-methylbenzenesulfonate 
• 1258948-58-1 torrubiellone B 

Relevant articles and documents

Directed orthometalation and the asymmetric total synthesis of N -deoxymilitarinone A and torrubiellone B

A diverted total synthesis (DTS) approach to the total synthesis of pyridone alkaloids N-deoxymilitarinone A (8) and torrubiellone B (10) has been developed. The common intermediate 14 was first assembled by a dual directed orthometalation process using a methoxymethyl group as directed metalation group. Other crucial steps include the assembly of polyenes under aldol condensation for DTS using general and concise strategy and diastereoselective synthesis of the syn-dimethyl array by an Evans aldol reaction.