123994-67-2 Usage
Classification
Synthetic purine nucleoside analog
Type of compound
Antineoplastic agent
Function
Antineoplastic activity
Mechanism
Interferes with the metabolism of DNA and RNA
Target conditions
Certain types of leukemia
Primary use
Treatment of acute lymphoblastic leukemia (ALL)
Target population
Children and young adults
Mode of action
Inhibition of damaged DNA and RNA repair
Outcome
Leads to the destruction of cancer cells
Administration route
Intravenous
Treatment approach
Often used in combination with other chemotherapy drugs
Purpose
To improve treatment outcomes in patients with leukemia
Side effects
Can cause serious side effects
Examples
Bone marrow suppression, infection, and gastrointestinal toxicity
Check Digit Verification of cas no
The CAS Registry Mumber 123994-67-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,9,9 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 123994-67:
(8*1)+(7*2)+(6*3)+(5*9)+(4*9)+(3*4)+(2*6)+(1*7)=152
152 % 10 = 2
So 123994-67-2 is a valid CAS Registry Number.
123994-67-2Relevant articles and documents
Structure-Activity Relationships of N2-Substituted Guanines as Inhibitors of HSV1 and HSV2 Thymidine Kinases
Hildebrand, Catherine,Sandoli, Daniele,Focher, Federico,Gambino, Joseph,Ciarrocchi, Giovanni,et al.
, p. 203 - 206 (2007/10/02)
A series of N2-phenylguanines was synthesized and tested for inhibition of the thymidine kinases encoded by Herpes simplex viruses type 1 and type 2.Compounds with hydrophobic, electron-attracting groups in the meta position of the phenyl ring