1239969-40-4

Basic information

• Product Name: ethyl 4-(2-fluoropyridin-4-ylamino)benzoate
• Synonyms: ethyl 4-(2-fluoropyridin-4-ylamino)benzoate
• CAS NO: 1239969-40-4
• Molecular Weight: 260.268
• Mol File: 1239969-40-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 4-(2-fluoropyridin-4-ylamino)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(2-fluoropyridin-4-ylamino)benzoate(1239969-40-4)
• EPA Substance Registry System: ethyl 4-(2-fluoropyridin-4-ylamino)benzoate(1239969-40-4)

Safety Data

• Hazardous Substances Data: 1239969-40-4(Hazardous Substances Data)

Upstream product

• 94-09-7 p-aminoethylbenzoate 
• 22282-70-8 2-fluoro-4-iodopyridine 

Relevant articles and documents

Metal assisted synthesis of mono and diamino substituted pyridines

A microwave assisted Buchwald-Hartwig amination protocol is reported for a series of dihalopyridine precursors. Using this procedure, selective substitution of one halogen by aryl or alkylamines is possible in very short time, usually 30 min. Mild base (K2CO3) can be used successfully, which broadens the substrate scope. The second halogen can then be substituted using alkylamines under nucleophilic substitution condition or via a Suzuki-Miyaura cross-coupling reaction. The target compounds are potential inducers of cardiomyogenesis as innovative approach in regenerative medicine.