124004-74-6

Basic information

• Product Name: 2,2,2-trifluoro-1-(2-fluorophenyl)ethanol
• Synonyms: 2,2,2-trifluoro-1-(2-fluorophenyl)ethanol
• CAS NO: 124004-74-6
• Molecular Formula: C₈H₆F₄O
• Molecular Weight: 194.1262528
• Mol File: 124004-74-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2,2-trifluoro-1-(2-fluorophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoro-1-(2-fluorophenyl)ethanol(124004-74-6)
• EPA Substance Registry System: 2,2,2-trifluoro-1-(2-fluorophenyl)ethanol(124004-74-6)

Safety Data

• Hazardous Substances Data: 124004-74-6(Hazardous Substances Data)

Usage

General Description

2,2,2-trifluoro-1-(2-fluorophenyl)ethanol is a chemical compound with the molecular formula C8H6F4O. It is a colorless liquid that is used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. 2,2,2-trifluoro-1-(2-fluorophenyl)ethanol contains a trifluoromethyl group attached to a benzene ring and an ethanol group, making it a versatile building block for the synthesis of various organic compounds. It is commonly used as a reagent in organic synthesis reactions and as a building block for the preparation of fluorinated compounds. Additionally, it has potential applications in the field of medicinal chemistry due to its unique structural features and fluorine substituents. Overall, 2,2,2-trifluoro-1-(2-fluorophenyl)ethanol is an important chemical with diverse applications in various industries.

Upstream product

• 124004-75-7 α,α,α-trifluoro-2-fluoroacetophenone 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 446-52-6 2-Fluorobenzaldehyde 
• 75-63-8 Bromotrifluoromethane 

Downstream Products

• 1135312-23-0 2,2,2-trifluoro-1-(2'-fluorophenyl)ethyl isobutyrate 
• 1135312-05-8 (R)-2,2,2-trifluoro-1-(2'-fluorophenyl)ethanol 
• 1135311-88-4 (S)-2,2,2-trifluoro-1-(2'-fluorophenyl)ethyl isobutyrate 
• 351002-89-6 1-(2-amino-5-phenyl)-2,2,2-trifluoroethanone 
• 124097-61-6 (S)-2,2,2-trifluoro-1-<2-<2-(methoxymethyl)-1-pyrrolidinyl>phenyl>ethanone 
• 124004-78-0 2,2,2-trifluoro-1-<2-<2-(methoxymethyl)-1-pyrrolidinyl>phenyl>ethanone 
• 124096-31-7 (R)-2,2,2-trifluoro-1-<2-(2-methyl-1-pyrrolidinyl)phenyl>ethanone 
• 124004-77-9 2,2,2-trifluoro-1-<2-(2-methyl-1-pyrrolidinyl)phenyl>ethanone 
• 124004-79-1 2,2,2-trifluoro-1-<2-(1-piperidinyl)phenyl>-1,1-ethanediol 
• 124004-76-8 2,2,2-trifluoro-1-<2-(1-pyrrolidinyl)phenyl>ethanone 
• 124004-75-7 α,α,α-trifluoro-2-fluoroacetophenone 

Relevant articles and documents

Asymmetric Hydrogenation of Aryl Perfluoroalkyl Ketones Catalyzed by Rhodium(III) Monohydride Complexes Bearing Josiphos Ligands

The asymmetric hydrogenation of 2,2,2-trifluoroacetophenones and aryl perfluoroalkyl ketones was developed using a unique, well-defined chloride-bridged dinuclear rhodium(III) complex bearing Josiphos-type diphosphine ligands. These complexes were prepared from [RhCl(cod)]2, Josiphos ligands, and hydrochloric acid. As catalyst precursors, they allow for the efficient and enantioselective synthesis (up to 99 % ee) of chiral secondary alcohols with perfluoroalkyl groups. This system does not require an activating base for the hydrogenation of 2,2,2-trifluoroacetophenones. Additionally, the enantioselective C=O hydrogenations of 2-phenyl-3-(haloacetyl)-indoles, a class of privileged structures in medicinal chemistry, is reported for the first time.

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula (“Formula One”).

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.