124051-65-6Relevant articles and documents
The Effect of Oxidizing Agents in the Preparation of 2,3,5-triaryl-2H-tetrazolium Salts from 1,3,5-triarylformazans
Penev, Kalin I.,Mequanint, Kibret
, p. 1655 - 1660 (2016)
Tetrazolium salts are a group of versatile molecules with a relatively limited application due to synthesis difficulty and high cost of production. Here, we have comparatively examined several approaches for the preparation of 2-(4-nitrophenyl)-3,5-diphenyl-2H-tetrazolium chloride (NTC), as a model tetrazolium salt, through the oxidation of 1-(4-nitrophenyl)-3,5-diphenylformazan (NF), by means of interphase oxidation, dehydrogenation, and direct chlorination. Our findings indicate that chlorination of NF with 1-chlorobenztriazole to be the best choice to prepare NTC from small-scale and scaled-up considerations.
PRODUCTION OF TETRAZOLIUM SALTS UNDER CONDITIONS OF PHASE-TRANSFER CATALYSIS
Zhivich, A. B.,Koldobskii, G. I.,Ostrovskii, V. A.
, p. 203 - 204 (2007/10/02)
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