1240649-46-0

Basic information

• Product Name: N-(2-oxo-2-(4-fluorophenyl)ethyl)-2-(5-bromo-2-methylphenyl)acetamide
• Synonyms: N-(2-oxo-2-(4-fluorophenyl)ethyl)-2-(5-bromo-2-methylphenyl)acetamide
• CAS NO: 1240649-46-0
• Molecular Weight: 364.214
• Mol File: 1240649-46-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-oxo-2-(4-fluorophenyl)ethyl)-2-(5-bromo-2-methylphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-oxo-2-(4-fluorophenyl)ethyl)-2-(5-bromo-2-methylphenyl)acetamide(1240649-46-0)
• EPA Substance Registry System: N-(2-oxo-2-(4-fluorophenyl)ethyl)-2-(5-bromo-2-methylphenyl)acetamide(1240649-46-0)

Safety Data

• Hazardous Substances Data: 1240649-46-0(Hazardous Substances Data)

Upstream product

• 854646-94-9 2-(5-bromo-2-methylphenyl)acetic acid 
• 456-00-8 2-amino-4'-fluoroacetophenone hydrochloride 

Downstream Products

• 1240649-48-2 2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiazole 

Relevant articles and documents

Discovery of canagliflozin, a novel C-glucoside with thiophene ring, as sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus (1)

We discovered that C-glucosides 4 bearing a heteroaromatic ring formed metabolically more stable inhibitors for sodium-dependent glucose cotransporter 2 (SGLT2) than the O-glucoside, 2 (T-1095). A novel thiophene derivative 4b-3 (canagliflozin) was a highly potent and selective SGLT2 inhibitor and showed pronounced anti-hyperglycemic effects in high-fat diet fed KK (HF-KK) mice.