1242182-96-2Relevant articles and documents
Direct synthesis of quinazolines through copper-catalyzed reaction of aniline-derived benzamidines
Ohta, Yusuke,Tokimizu, Yusuke,Oishi, Shinya,Fujii, Nobutaka,Ohno, Hiroaki
supporting information; experimental part, p. 3963 - 3965 (2010/11/17)
A novel synthesis of 2-phenyl-4-[(triisopropylsilyl)methyl]quinazolines from monosubstituted arenes has been developed. Treatment of N-phenylbenzamidines with 5-nitro-1-[(triisopropylsilyl)ethynyl]-1,2- benziodoxol-3(1H)-one and K2CO3 in the presence of a catalytic amount of CuBr in benzene gives 2-phenyl-4-[(triisopropylsilyl)methyl] quinazolines in moderate to good yields.