124302-98-3Relevant articles and documents
Convenient synthesis of racemic 4,4-difluoro glutamic acid derivatives via Michael-type additions of Ni(II)-complex of dehydroalanine Schiff bases
Tokairin, Yoshinori,Soloshonok, Vadim A.,Konno, Hiroyuki,Moriwaki, Hiroki,R?schenthaler, Gerd-Volker
, (2019)
Michael-type addition reactions of Ni(II)-complex of a dehydroalanine Schiff base and ethyl bromodifluoroacetate in the presence of copper for the synthesis of racemic 4,4,-difluoroglutamic acid derivatives were developed. These reactions proceeded smooth
Highly efficient catalytic synthesis of α-amino acids under phase-transfer conditions with a novel catalyst/substrate pair
Belokon, Yuri N.,Kochetkov, Konstantin A.,Churkina, Tatiana D.,Ikonnikov, Nikolai S.,Larionov, Oleg V.,Harutyunyan, Syuzanna R.,Vyskocil, Stepan,North, Michael,Kagan, Henri B.
, p. 1948 - 1951 (2007/10/03)
A facile and fast enantioselective synthesis of α-amino acids with high ee values was achieved by the asymmetric alkylation of the glycine derivative 1 under phase-transfer conditions with (R)-2-amino-2′-hydrozy-1,1′-binaphthyl (NOBIN; see sceme). The ee value of the amino acid products. This occures as a results of a significant positive nonlinear effect in the alkylation reaction.
