124337-30-0

Basic information

• Product Name: E-(R)-(-)-1,4-diphenyl-4-methoxymethoxy-1-buten-3-one
• Synonyms: E-(R)-(-)-1,4-diphenyl-4-methoxymethoxy-1-buten-3-one
• CAS NO: 124337-30-0
• Molecular Weight: 282.339
• Mol File: 124337-30-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: E-(R)-(-)-1,4-diphenyl-4-methoxymethoxy-1-buten-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: E-(R)-(-)-1,4-diphenyl-4-methoxymethoxy-1-buten-3-one(124337-30-0)
• EPA Substance Registry System: E-(R)-(-)-1,4-diphenyl-4-methoxymethoxy-1-buten-3-one(124337-30-0)

Safety Data

• Hazardous Substances Data: 124337-30-0(Hazardous Substances Data)

Upstream product

• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 917-54-4 methyllithium 
• 124312-32-9 Z-(R)-(-)-1,4-diphenyl-4-methoxymethoxy-1-buten-3-one 
• 124312-31-8 (E)-(R)-1-Methoxymethoxy-1,4-diphenyl-but-3-en-2-ol 
• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 611-71-2 (R)-Mandelic Acid 
• 124312-30-7 (R)-(-)-mandelic acid methoxymethyl ether methoxymethyl ester 
• 107536-09-4 (2R)-2-methoxymethoxy-3-phenylacetaldehyde 

Downstream Products

• 124312-33-0 (1R,4S)-1,4-diphenyl-1-methoxymethoxypentan-2-one 
• 124312-34-1 (1R,4R)-1-Methoxymethoxy-1,4-diphenyl-pentan-2-one 
• 93-53-8 (R)-2-phenylpropanal 

Relevant articles and documents

COORDINATIVELY INDUCED 1,4-DIASTEREOSELECTION IN THE REACTION OF ACYCLIC α,β-ENONES WITH ORGANOCOPPER REAGENTS. A NEW TYPE OF ORGANOCOPPER REAGENT

A test has been made of a stereochemical prediction for conjugate addition based on the intermediacy of d,?*-complexes in the reaction of organocopper reagents with α,β-enones.The chiral α,β-enone 7 has been synthesized and subjected to reaction with various methyl cuprate reagents.Under conditions favorable to lithium chelation to the α-alkoxycarbonyl system of 7, conjugate addition to 7 was found to proceed with high (13:1 to 33:1) 1,4-diastereoselectivity, the configuration of the major diastereomer being that predicted by the d,?*-complex model.A new and especially diastereoselective reagent has been generated by the reaction of LiCuMe2 with 0.3 equivalent of water, a possible structure for which is presented.