1245707-61-2

Basic information

• Product Name: C₂₆H₃₀ClN₅O₄
• Synonyms: C₂₆H₃₀ClN₅O₄
• CAS NO: 1245707-61-2
• Molecular Weight: 512.008
• Mol File: 1245707-61-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₀ClN₅O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₀ClN₅O₄(1245707-61-2)
• EPA Substance Registry System: C₂₆H₃₀ClN₅O₄(1245707-61-2)

Safety Data

• Hazardous Substances Data: 1245707-61-2(Hazardous Substances Data)

Upstream product

• 931-53-3 Cyclohexyl isocyanide 
• 18523-47-2 3-azidopropanoic acid 
• 104-86-9 4-chlorobenzylamine 
• 1076-95-5 p-methoxyphenylglyoxal 

Downstream Products

• 1245707-69-0 N-cyclohexyl 4-(4-chlorobenzyl)-2-(4-methoxyphenyl)-5-oxo-4,5,6,7-tetrahydro-1H-1,4-diazepine-3-carboxamide 

Relevant articles and documents

Synthesis of pseudopeptidic (S)-6-amino-5-oxo-1,4-diazepines and (S)-3-benzyl-2-oxo-1,4-benzodiazepines by an Ugi 4CC Staudinger/aza-Wittig sequence

Sequential Ugi reaction between p-substituted arylglyoxals, alkylamines, cyclohexyl isocyanide and 3-azido-(S)-2-(tert-butoxycarbonylamino)propanoic acid, followed by a Staudinger/aza-Wittig cyclization in the presence of triphenylphosphine, gave rise to enantiomerically pure N-cyclohexyl 4-alkyl-2-aryl-5-oxo-(S)-6-(tert-butoxycarbonylamino)-4,5,6,7-tetrahydro-1H-1, 4-diazepine-3-carboxamides, that can be useful for new drug design. By the same sequence, p-substituted benzaldehydes, 2-aminobenzophenone, cyclohexyl isocyanide and (S)-3-phenyl-2-azidopropionic acid gave rise to N-cyclohexyl 2-((S)-3-benzyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-1-yl)-(R/S) -2-arylacetamides.