125-72-4 Usage
Description
LEVORPHANOL TARTRATE NARCOTIC ANALGESIC is an orally active synthetic morphine analog that serves as a potent narcotic analgesic. It is a controlled substance known for its effectiveness in providing pain relief and is commonly used under the brand name Levo-Dromoran (Valeant).
Uses
Used in Pharmaceutical Industry:
LEVORPHANOL TARTRATE NARCOTIC ANALGESIC is used as a potent analgesic for the management of moderate to severe pain. It is particularly effective in cases where other pain relief medications may not provide sufficient relief. As a narcotic, it works by binding to opioid receptors in the brain, reducing the perception of pain and providing a sense of relaxation.
Used in Pain Management:
LEVORPHANOL TARTRATE NARCOTIC ANALGESIC is used as a pain management tool for patients suffering from chronic or acute pain conditions. Its strong analgesic properties make it a valuable option for healthcare professionals when treating patients with severe pain that may not respond well to other medications.
Used in Palliative Care:
LEVORPHANOL TARTRATE NARCOTIC ANALGESIC is also used in palliative care to alleviate pain and discomfort in patients with terminal illnesses. Its potent analgesic effects can help improve the quality of life for these patients by providing significant pain relief and reducing anxiety associated with their condition.
It is important to note that LEVORPHANOL TARTRATE NARCOTIC ANALGESIC is a controlled substance, and its use should be carefully monitored and prescribed by healthcare professionals to minimize the risk of misuse, addiction, and other potential side effects.
Clinical Use
Levorphanol is a potent μ agonist (approximately sixfold greater than morphine), and its uses, side
effects, and physical dependence liability are like those of oxymorphone or hydromorphone.
Levorphanol is available in oral, subcutaneous, and intravenous dosage forms. The oral dose of
levorphanol is approximately twice the parenteral dose. This drug is unique among the μ agonists
in that its analgesic duration of action is 4 to 6 hours, whereas its clearance half-life is 11.4 hours.
Thus, effective analgesic doses of this agent can lead to a buildup of the drug in the body and
result in excessive sedation.
Check Digit Verification of cas no
The CAS Registry Mumber 125-72-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 125-72:
(5*1)+(4*2)+(3*5)+(2*7)+(1*2)=44
44 % 10 = 4
So 125-72-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;/m0./s1
125-72-4Relevant articles and documents
METHODS FOR PREPARING LEVORPHANOL AND RELATED COMPOUNDS, AND COMPOSITIONS THEREOF
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Paragraph 0177-0182, (2020/04/29)
A method for producing substantially pure levorphanol and related compounds, when compared to the conventional process, is provided. In particular, a method for producing substantially pure levorphanol tartrate dihydrate is described. Also described are compositions comprising levorphanol and related compounds, particularly compositions comprising levorphanol tartrate dihydrate, levomethorphan, and norlevorphanol in which the levomethorphan and norlevorphanol are present in the composition in reduced levels.
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