1253227-74-5Relevant articles and documents
Effective total synthesis of schaftoside
Shang, Chengxiang,Zhao, Chuanfang,Nie, Pengpeng,Liu, Jun,Du, Yuguo
, (2021)
A short and scalable approach toward the total synthesis of schaftoside, a naturally occurring bioactive C-glycosylflavone, has been developed from readily available (±)-naringenin. The highlights of this work are double Lewis acid promoted O→C rearrangement to form C-glycoside, oxidative dehydrogenation to construct flavone ring, and easy operational process to make the target product in multigram-scale.