1253517-85-9Relevant articles and documents
Synthesis of some biologically active pyrazolones
Gaikar,Gadhave,Karale
, p. 325 - 328 (2012/01/06)
1-(4-(Pyridin-2-yl) benzyl)-3-propyl-1W-pyrazol-5(4H)-one 1 was treated with heterocyclic aldehydes such as 2-chloro-3-formylquinoline 2,4-formylpyrazole 3 and 3- formylchromone 4, in acetic acid to get (4Z)-1 -(4-pyridin-2-yl) benzyl-4-((2-chloroquinolin- 3-yl) methylene)-3-propyl-1H- pyrazol-5(4H)-ones5, (4Z)-1-(4-(pyridin-2-yl) benzyl)-4-((1- phenyl-1H-pyrazol-4-yl) methylene)-3-propyl-1H-pyrazol-5(4H)-ones 6 and (4Z)-1-(4- (pyndin-2-yl) benzyl)-4-((4-oxo-4H-chromen-3-yl) methylene)-3-propyl- 1H-pyrazol-5(4H)- ones 7. These compounds were synthesized by conventional as well as by ultrasound irradiation. Synthesized compounds were characterized by 1H NMR, mass and IR spectral techniques. They were also screened for antimicrobial activity.