1253732-02-3

Basic information

• Product Name: 2-{4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-3,5-dimethyl-phenyl}-6-morpholin-4-yl-3H-quinazolin-4-one
• Synonyms: 2-{4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-3,5-dimethyl-phenyl}-6-morpholin-4-yl-3H-quinazolin-4-one
• CAS NO: 1253732-02-3
• Molecular Weight: 509.721
• Mol File: 1253732-02-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-3,5-dimethyl-phenyl}-6-morpholin-4-yl-3H-quinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-3,5-dimethyl-phenyl}-6-morpholin-4-yl-3H-quinazolin-4-one(1253732-02-3)
• EPA Substance Registry System: 2-{4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-3,5-dimethyl-phenyl}-6-morpholin-4-yl-3H-quinazolin-4-one(1253732-02-3)

Safety Data

• Hazardous Substances Data: 1253732-02-3(Hazardous Substances Data)

Upstream product

• 1044872-73-2 4-[2-(tert-butyldimethylsilanyloxy)ethoxy]-3,5-dimethylbenzaldehyde 
• 93246-58-3 2-amino-5-(morpholin-4-yl)benzamide 

Downstream Products

• 1253732-01-2 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-6-morpholinoquinazolin-4(3H)-one 

Relevant articles and documents

NOVEL ANTI-INFLAMMATORY AGENTS

Disclosed are methods of regulating interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides novel synthetic quinazolone compounds, as well as pharmaceutical compositions comprising those compounds.