1254939-30-4

Basic information

• Product Name: 2-(4-bromophenyl)-1,1,1-trifluoropent-4-en-2-ol
• Synonyms: 2-(4-bromophenyl)-1,1,1-trifluoropent-4-en-2-ol
• CAS NO: 1254939-30-4
• Molecular Weight: 295.099
• Mol File: 1254939-30-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-bromophenyl)-1,1,1-trifluoropent-4-en-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenyl)-1,1,1-trifluoropent-4-en-2-ol(1254939-30-4)
• EPA Substance Registry System: 2-(4-bromophenyl)-1,1,1-trifluoropent-4-en-2-ol(1254939-30-4)

Safety Data

• Hazardous Substances Data: 1254939-30-4(Hazardous Substances Data)

Upstream product

• 16184-89-7 4'-bromo-2,2,2-trifluoroacetophenone 
• 1730-25-2 allylmagnesium bromide 
• 1122-91-4 4-bromo-benzaldehyde 
• 80418-12-8 1-(4-bromo-phenyl)-2,2,2-trifluoro-ethanol 
• 24850-33-7 allyltributylstanane 

Relevant articles and documents

Synthesis of Perfluoroalkyl-Substituted Vinylcyclopropanes by Way of Enhanced Neighboring Group Participation

A simple, high yielding, two-step, one-pot protocol for the preparation of trifluoromethyl-substituted vinylcyclopropanes from α-CF3 homoallyl alcohols is disclosed. Destabilization of the cationic intermediate by the electron-withdrawing CF3 group greatly enhances neighboring group participation of the alkene, allowing ring closure to predominate. The reaction can be extended to the difluoromethyl and pentafluoroethyl group, enabling the preparation of a diverse array of fluoroalkyl-substituted vinylcyclopropanes. A diverse array of fluoroalkyl-substituted vinylcyclopropanes are prepared in a simple, high-yielding, two-step, one-pot protocol by means of cationic ring-closure.