1255662-58-8Relevant articles and documents
Magnesium coordination-directed N-selective stereospecific alkylation of 2-pyridones, carbamates, and amides using α-halocarboxylic acids
Fang, Yuan-Qing,Bio, Matthew M.,Hansen, Karl B.,Potter, Matthew S.,Clausen, Andrew
supporting information; experimental part, p. 15525 - 15527 (2011/02/21)
A general inversion-stereospecific, N-selective alkylation of substituted 2-pyridones (and analogues), amides, and carbamates using chiral α-chloro- or bromocarboxylic acids in the presence of KOt-Bu (or KHMDS) and Mg(Ot-Bu)2 is reported. The r