1256584-78-7

Basic information

• Product Name: 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid
• Synonyms: 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid
• CAS NO: 1256584-78-7
• Molecular Formula: C30H36N4O3
• Molecular Weight: 500.63184
• EINECS: -0
• Mol File: 1256584-78-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 725.9±60.0 °C(Predicted)
• Appearance: /
• Density: 1.27±0.1 g/cm3(Predicted)
• PKA: 3.18±0.10(Predicted)
• CAS DataBase Reference: 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid(1256584-78-7)
• EPA Substance Registry System: 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid(1256584-78-7)

Safety Data

• Hazardous Substances Data: 1256584-78-7(Hazardous Substances Data)

Usage

Description

6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid is a complex organic compound characterized by its unique molecular structure. It is an intermediate in the synthesis of Alectinib (C183360), a pharmaceutical agent with significant therapeutic potential.

Uses

Used in Pharmaceutical Industry:
6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid is used as a key intermediate in the production of Alectinib, a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor. 6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid is crucial for the development of targeted cancer therapies, as Alectinib is capable of blocking the resistant gatekeeper mutant, leading to a reduction in cell growth and offering a promising treatment option for patients with certain types of cancer.