1256834-13-5 Usage
Description
4-Bromo-6-chloronicotinic acid is an organic compound characterized by the presence of a bromo and a chloro substituent on the pyridine ring. It is a key intermediate in the synthesis of various naphthyridine derivatives and related heterocycles, which have potential applications in the treatment of BAF-mediated disorders.
Uses
Used in Pharmaceutical Industry:
4-Bromo-6-chloronicotinic acid is used as a key intermediate in the synthesis of naphthyridine derivatives and related heterocycles for the treatment of BAF-mediated disorders such as viral infections and cancer. These compounds have shown potential in modulating the activity of BAF complexes, which play a crucial role in various cellular processes and are implicated in the pathogenesis of these disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 1256834-13-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,6,8,3 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1256834-13:
(9*1)+(8*2)+(7*5)+(6*6)+(5*8)+(4*3)+(3*4)+(2*1)+(1*3)=165
165 % 10 = 5
So 1256834-13-5 is a valid CAS Registry Number.
1256834-13-5Relevant articles and documents
HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS
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Paragraph 00249, (2019/03/15)
Compounds having the following formula (I) or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, including IRAK-4 inhibition.
