1260507-57-0

Basic information

• Product Name: tert-butyl (S)-2-[(S)-4-benzyl-2-oxo-1,3-oxazolidin-3-ylcarbonyl]pyrrolidine-1-carboxylate
• Synonyms: tert-butyl (S)-2-[(S)-4-benzyl-2-oxo-1,3-oxazolidin-3-ylcarbonyl]pyrrolidine-1-carboxylate
• CAS NO: 1260507-57-0
• Molecular Weight: 374.437
• Mol File: 1260507-57-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl (S)-2-[(S)-4-benzyl-2-oxo-1,3-oxazolidin-3-ylcarbonyl]pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (S)-2-[(S)-4-benzyl-2-oxo-1,3-oxazolidin-3-ylcarbonyl]pyrrolidine-1-carboxylate(1260507-57-0)
• EPA Substance Registry System: tert-butyl (S)-2-[(S)-4-benzyl-2-oxo-1,3-oxazolidin-3-ylcarbonyl]pyrrolidine-1-carboxylate(1260507-57-0)

Safety Data

• Hazardous Substances Data: 1260507-57-0(Hazardous Substances Data)

Upstream product

• 147-85-3 L-proline 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 883565-15-9 C₁₅H₂₅NO₅ 
• 74108-10-4 C₆H₁₅N*C₁₀H₁₇NO₄ 
• 75-65-0 tert-butyl alcohol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 

Downstream Products

• 1260507-58-1 (S)-3-((S)-1-benzyl-2-hydroxy ethyl)-2,4-dioxo-1,3-diazabicyclo[3.3.0]octane 

Relevant articles and documents

Practical one-pot double functionalizations of proline

Solubilization of proline as the triethylammonium salt allows N-protection (as the Boc, Cbz or Moc derivative) and subsequent esterification or amidation of the carboxy terminus to be performed in an efficient one-pot fashion. Based on this concept, highly practical protocols were developed to prepare a series of proline derivatives (including Pro-Ser dipetides, Weinreb amides and N-protected proline esters), which are important intermediates, for instance, for the synthesis of proline-derived peptides, chiral reagents and catalysts for asymmetric synthesis. Georg Thieme Verlag Stuttgart - New York.