1260539-62-5

Basic information

• Product Name: 4-{4-iodo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl}-3-nitrobenzonitrile
• Synonyms: 4-{4-iodo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl}-3-nitrobenzonitrile
• CAS NO: 1260539-62-5
• Molecular Weight: 459.126
• Mol File: 1260539-62-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{4-iodo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl}-3-nitrobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{4-iodo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl}-3-nitrobenzonitrile(1260539-62-5)
• EPA Substance Registry System: 4-{4-iodo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl}-3-nitrobenzonitrile(1260539-62-5)

Safety Data

• Hazardous Substances Data: 1260539-62-5(Hazardous Substances Data)

Upstream product

• 939-80-0 4-chloro-3-nitrobenzonitrile 
• 1160502-30-6 4-iodo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine 
• 22282-70-8 2-fluoro-4-iodopyridine 

Downstream Products

• 1260539-61-4 3-Amino-4-{4-iodo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzonitrile 
• 1260539-63-6 3-Amino-4-{4-iodo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzamide 

Relevant articles and documents

AZABICYCLO COMPOUND AND SALT THEREOF

It is intended to provide a novel azabicyclo compound which exhibits both HSP90 inhibitory activity and cell proliferation inhibitory effect. Specifically disclosed is a compound represented by the following general formula (I) or a salt thereof: wherein X1 represents CH or N; any one of X2, X3 and X4 represents N, and the others represent CH; any one or two of Y1, Y2, Y3 and Y4 represent C—R4, and the others are the same or different and represent CH or N; R1 represents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S and O; R2 represents an alkyl group having 1 to 6 carbon atoms, or the like; and R3 and R4 represent —CO—R5 or the like.