1260619-38-2

Basic information

• Product Name: (R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride
• Synonyms: (R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride;(5R)-Hexahydro-5-methyl-1H-1,4-diazepine-1-carboxylic acid 1,1-dimethylethyl ester;(R)-1-Boc-5-methyl-1,4-diazepane;TERT-BUTYL (5R)-5-METHYL-1,4-DIAZEPANE-1-CARBOXYLATE
• CAS NO: 1260619-38-2
• Molecular Formula: C11H22N2O2
• Molecular Weight: 214.31
• EINECS: -0
• Mol File: 1260619-38-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 288.3±23.0 °C(Predicted)
• Appearance: /
• Density: 0.980±0.06 g/cm3(Predicted)
• PKA: 10.51±0.40(Predicted)
• CAS DataBase Reference: (R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride(1260619-38-2)
• EPA Substance Registry System: (R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride(1260619-38-2)

Safety Data

• Hazardous Substances Data: 1260619-38-2(Hazardous Substances Data)

Usage

Description

(R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride is a complex organic compound characterized by its unique molecular structure. It is a derivative of benzoxazole with a chloro substituent at the 5-position and a 5-methyl-1,4-diazepan-1-yl group attached at the 2-position. (R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride is typically obtained as a hydrochloride salt, which contributes to its stability and solubility in various solvents. Its chemical properties and structural features make it a valuable intermediate in the synthesis of pharmaceutical compounds.

Uses

Used in Pharmaceutical Industry:
(R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride is used as an intermediate in the synthesis of suvorexant (S870000), a selective dual orexin receptor antagonist. This application is significant because suvorexant is a medication used to treat insomnia by targeting the orexin system in the brain, which is involved in the regulation of wakefulness. The compound's role in the synthesis process is crucial for the development of effective treatments for sleep disorders.