1260667-91-1 Usage
Description
5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carbaldehyde is a heterocyclic chemical compound with the molecular formula C8H8N2O. It features a pyrrolopyrazole ring system and an aldehyde functional group, which contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carbaldehyde is used as a building block for the synthesis of various bioactive molecules and pharmaceutical intermediates. Its unique structure allows for the development of new drugs with potential therapeutic effects.
Used in Agrochemical Industry:
5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carbaldehyde is also utilized in the development of new agrochemicals, where its properties can be harnessed to create effective products for agricultural applications.
Used as a Precursor in Industrial Synthesis:
5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carbaldehyde may have potential industrial applications as a precursor in the synthesis of various fine chemicals, contributing to the production of specialty products.
Further research and development are necessary to fully explore and unlock the capabilities of 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carbaldehyde in these and potentially other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1260667-91-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,0,6,6 and 7 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1260667-91:
(9*1)+(8*2)+(7*6)+(6*0)+(5*6)+(4*6)+(3*7)+(2*9)+(1*1)=161
161 % 10 = 1
So 1260667-91-1 is a valid CAS Registry Number.
1260667-91-1Relevant articles and documents
Synthesis of (5,6-dihydro-4h-pyrrolo[1,2-b]pyrazol-3-yl)methanamine
Bai, Zhong-Gang,Qi, Hui,Zhang, Qun-Zheng,Ma, Yu,Pan, Qing,Zhang, Xun-Li
, p. 1923 - 1930 (2017)
This short paper reports the development of a new method for the synthesis of (5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)methanamine. Pyrazole was initially protected with an N-SEM protective group, followed by alkylation at C-5 position with 1-bromo-3-chloropropane. Following SEM deprotection, the intramolecular ring was closed and then a bromine atom (Br) was introduced with N-bromosuccinimide (NBS) by electrophilic aromatic substitution (SEAr), forming 3-bromo-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole. The Br group was subsequently converted into aldehyde group, then into oxime. The final step of hydrogenation resulted in the desired product. The overall yield through the 8-step reaction process was found to be 29.4%. The intermediates and final product were identified by HPLC-MS and 1H NMR. This development provides a novel synthetic route to the formation of 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole skeleton.
