1263313-63-8

Basic information

• Product Name: 4-chloro-N-[2-(3-methyl-butyryl)-phenyl]-benzene-sulfonamide
• CAS NO: 1263313-63-8
• Molecular Weight: 351.854
• Mol File: 1263313-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-N-[2-(3-methyl-butyryl)-phenyl]-benzene-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-N-[2-(3-methyl-butyryl)-phenyl]-benzene-sulfonamide(1263313-63-8)
• EPA Substance Registry System: 4-chloro-N-[2-(3-methyl-butyryl)-phenyl]-benzene-sulfonamide(1263313-63-8)

Safety Data

• Hazardous Substances Data: 1263313-63-8(Hazardous Substances Data)

Upstream product

• 98-64-6 4-Chlorobenzenesulfonamide 
• 582-62-7 3-methyl-1-phenylbutan-1-one 

Downstream Products

• 1263313-85-4 1-(4-chloro-benzenesulfonyl)-2-isobutyl-1H-indole 
• 56514-76-2 1-(2-aminophenyl)-3-methylbutan-1-one 
• 147770-03-4 3-methyl-1-(2-piperidin-1-yl-phenyl)-butan-1-one 
• 1263313-67-2 1-(4-chloro-benzenesulfonyl)-3-isobutyl-1H-indole 
• 1263313-74-1 4-chloro-N-[2-(4-methyl-pent-1-ynyl)-phenyl]-benzenesulfonamide 

Relevant articles and documents

Palladium-catalyzed intermolecular directed C-H amidation of aromatic ketones

Pd-catalyzed directed ortho C-H amidation of aromatic ketones with both sulfonamides and amides has been accomplished. The use of an electron-deficient Pd complex, Pd(OTf)2, is crucial for the success of this transformation. Some key intermediates of the reaction, that is, the cyclopalladation complexes of ketones, have been characterized by X-ray crystallography. Experimental analysis of these palladacycles and also the experimental results with N-methyl sulfonamides indicate that the new reaction does not seem to proceed through a nitrene intermediate. The utility of the newly developed reaction was demonstrated for the synthesis of useful organic intermediates such as 2- and 3-alkyl indoles and 2-aminophenyl ketones.