126799-89-1

Basic information

• Product Name: 1H-1,2,3-Triazole-4,5-dicarboxylic acid, 1-[(4-methylphenyl)methyl]-, dimethyl ester
• CAS NO: 126799-89-1
• Molecular Formula: C14H15N3O4
• Molecular Weight: 289.291
• Mol File: 126799-89-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-1,2,3-Triazole-4,5-dicarboxylic acid, 1-[(4-methylphenyl)methyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,3-Triazole-4,5-dicarboxylic acid, 1-[(4-methylphenyl)methyl]-, dimethyl ester(126799-89-1)
• EPA Substance Registry System: 1H-1,2,3-Triazole-4,5-dicarboxylic acid, 1-[(4-methylphenyl)methyl]-, dimethyl ester(126799-89-1)

Safety Data

• Hazardous Substances Data: 126799-89-1(Hazardous Substances Data)

Upstream product

• 17271-89-5 4-methylphenylmethylazide 
• 762-42-5 dimethyl acetylenedicarboxylate 

Relevant articles and documents

1,2,3-Triazole[4,5-d]pyridazines - IV. Preparation and adenosine receptor binding of new 4 and/or 7 aminoderivatives

This paper reports the continuation of the studies on the 4-aminosubstituted 1,2,3-triazole[4,5-d]pyridazine derivatives which had shown binding affinity towards adenosine receptors. Biological results confirmed the greater activity of a benzyl substituent in the 1 position and the receptorial stereoselectivity related to the higher and more selective A1 affinity of the 4-D(+)-α-methylbenzylamino enantiomer 1b. The 4-phenylhydrazino substituent has shown an interesting binding activity about equipotent towards A1 and A2 receptorial sites. A surprisingly elevated A1 affinity (Ki = 7 nM), 440 fold higher than A2 affinity, is presented by compound 1d, bearing a m-toluidino substituent.