126938-14-5

Basic information

• Product Name: 4-Methylumbelliferylbeta-D-galactopyranoside-6-sulfatesodiumsalt
• Synonyms: 4-methylumbelliferyl-6-thiogalactoside;4MU B-D-GALACTOPYRANOSIDE-6-SULFATE SODIUM SALT;4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Discontinued See: M334481;4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one
• CAS NO: 126938-14-5
• Molecular Formula: C16H18O11S
• Molecular Weight: 418.3725
• EINECS: 1533716-785-6
• Product Categories: Carbohydrates & Derivatives;Fluorescent Labels & Indicators;substrate
• Mol File: 126938-14-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 196-200°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.676 g/cm³
• Refractive Index: 1.645
• Storage Temp.: Store at 4
• Solubility: Water
• CAS DataBase Reference: 4-Methylumbelliferylbeta-D-galactopyranoside-6-sulfatesodiumsalt(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylumbelliferylbeta-D-galactopyranoside-6-sulfatesodiumsalt(126938-14-5)
• EPA Substance Registry System: 4-Methylumbelliferylbeta-D-galactopyranoside-6-sulfatesodiumsalt(126938-14-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 126938-14-5(Hazardous Substances Data)

Usage

Description

4-Methylumbelliferylbeta-D-galactopyranoside-6-sulfatesodiumsalt is a white to off-white solid that serves as a fluorogenic substrate for galactose-6-sulfate sulfatase. It is used in the diagnosis of Morquio disease type A and Mucopolysaccharidosis IV A, which are lysosomal storage disorders caused by a deficiency of this enzyme.

Uses

Used in Medical Diagnostics:
4-Methylumbelliferylbeta-D-galactopyranoside-6-sulfatesodiumsalt is used as a fluorogenic substrate for the diagnosis of Morquio disease type A and Mucopolysaccharidosis IV A. It helps in determining the activity of galactose-6-sulfate sulfatase, an enzyme involved in the degradation of glycosaminoglycans, which are essential for maintaining the structural integrity of various tissues.
Used in Research and Development:
In the research industry, 4-Methylumbelliferylbeta-D-galactopyranoside-6-sulfatesodiumsalt is used as a tool to study the activity and function of galactose-6-sulfate sulfatase. This helps researchers understand the underlying mechanisms of lysosomal storage disorders and develop potential therapeutic strategies for their treatment.
Used in Quality Control:
4-Methylumbelliferylbeta-D-galactopyranoside-6-sulfatesodiumsalt is also used in the quality control of diagnostic assays and kits. It serves as a standard to ensure the accuracy and reliability of the tests used for the diagnosis of Morquio disease type A and Mucopolysaccharidosis IV A.

InChI:InChI=1/C16H18O11S/c1-7-4-12(17)26-10-5-8(2-3-9(7)10)25-16-15(20)14(19)13(18)11(27-16)6-24-28(21,22)23/h2-5,11,13-16,18-20H,6H2,1H3,(H,21,22,23)/t11-,13+,14+,15-,16-/m1/s1