126956-59-0

Basic information

• Product Name: 1-Methylsulfanyl-1-phenyl-propan-2-ol
• CAS NO: 126956-59-0
• Molecular Weight: 182.287
• Mol File: 126956-59-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Methylsulfanyl-1-phenyl-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methylsulfanyl-1-phenyl-propan-2-ol(126956-59-0)
• EPA Substance Registry System: 1-Methylsulfanyl-1-phenyl-propan-2-ol(126956-59-0)

Safety Data

• Hazardous Substances Data: 126956-59-0(Hazardous Substances Data)

Upstream product

• 1439-07-2 trans-Stilbene oxide 
• 873-66-5 1-propenylbenzene 
• 23355-97-7 1-phenylpropylene oxide 
• 5188-07-8 sodium thiomethoxide 

Downstream Products

• 135511-34-1 (1RS,2SR)-1-methyl-2-(methylthio)-2-phenyl-1-(trimethylsilyloxy)ethane 
• 135511-45-4 1-methyl-2-(methylsulfinyl)phenethylacetate 
• 135511-44-3 1-methyl-2-(methylsulfinyl)-2-phenyl-1-(trimethylsilyloxy)ethane 
• 126956-72-7 1-Methanesulfinyl-1-phenyl-propan-2-ol 
• 135511-35-2 (1RS,2SR)-1-methyl-2-(methylthio)phenethylacetate 
• 126956-64-7 (1RS,2SR)-1-methyl-2-(methylthio)-2-phenyl-1-(triphenylsilyloxy)ethane 

Relevant articles and documents

Enantioselective Oxidation of β-Hydroxythioethers. Synthesis of Optically Active Alcohols and Epoxides

Optically pure β-hydroxysulfoxides may be obtained by direct oxidation of the parent thioethers with the modified Sharpless reagent developed in our laboratory.Necessary requisites for a successful asymmetric oxidation are both the protection of the OH function and the largest possible difference in size of the two groups linked to the thioether sulfur.This latter condition is fulfilled by using S-methyl derivatives.Examples referring to the oxidation of various S-methyl-β-hydroxythioethers, characterized by e.e. values up to 80percent, which may be further increased (>98percent) by crystallization, are presented.Results concerning the synthesis of optically active epoxides and alcohols starting from β-hydroxysulfoxides are also presented which, in some cases, allows the absolute configuration of the parent sulfoxide to be established.