126993-07-5Relevant articles and documents
Room-Temperature Practical Copper-Catalyzed Amination of Aryl Iodides
Deldaele, Christopher,Evano, Gwilherm
, p. 1319 - 1328 (2016/04/20)
An efficient and highly practical procedure is reported for the Ullmann-Goldberg-type copper-catalyzed amination of aryl iodides. By using a combination of copper iodide and proline in the presence of an excess of an amine, a wide range of aryl iodides can be readily aminated at room temperature. The reaction proceeds well regardless of the electronic properties of the starting aryl iodide and the amination products can be obtained without the need for purification by column chromatography in most cases. Owing to its efficiency and the mildness of the reaction conditions, this amination could also be extended to the amination of complex aryl iodides at room temperature.
METHODS FOR PREPARING ANTIPROLIFERATIVE 5-SUBSTITUTED PYRIMIDONE COMPOUNDS
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, (2008/06/13)
Intermediates for preparing derivatives of 5-thia- and5-selenopyrimidinone which are useful as inhibitors of the enzymes glydnamide ribonucleotide formyl transferase (GARFT) and amino imidazole carboxamide ribonucleotide formyl transferase (AICARFT). The present invention is also directed to methods of preparing these intermediates
NEW APPROACHES TO SYNTHESIS OF N-ARYL-1,3-OXAZOLIDINES AND N-ARYL-1,3-TETRAHYDROOXAZINES
Zorina, L. N.,Safiev, O. G.,Rakhmankulov, D. L.,Paushkin, Ya. M.
, p. 295 - 298 (2007/10/02)
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